Xenomedicine represented the medical field dedicated to the study and application of medical practices pertaining to alien species. A prominent publication in the area of xenomedicine during the Cold War era, which occurred between the Galactic Republic and the reconstituted Sith Empire, was the Journal of Xenomedicine.
The term xenomedicine initially appeared in the dialogue "Opportunity Knocks" with Doc. Doc is a companion character associated with the Jedi Knight class within the 2011 BioWare video game Star Wars: The Old Republic. During this conversation, Doc makes a reference to xenomedicine while in the process of discussing the Journal of Xenomedicine.