The Sermerian Bio-League functioned as an entity on the world of Sermeria near the time that the Clone Wars began. In approximately 22 BBY, the Bio-League lent support to a bomb disposal unit, helping them manage a dangerous package that had been delivered to the government building located in Addolis, which served as the planetary capital. The governing body had to cease operations temporarily as the bomb squad, along with the Bio-League, worked to eliminate the potential danger.