Culpharm, a pharmaceutical enterprise, functioned within the Cularin system as the Galactic Republic neared its end.
Around 32 BBY, the disappearance of several specimen samples prompted Culpharm's security chief, Carlitina Semla, to enlist the services of the Heroes of Cularin for an inquiry. Soon after, Culpharm received intelligence indicating that Genasys, a competing firm, intended to collaborate with the Cerean Higgie Sethven in the creation of a novel pharmaceutical product. Culpharm's reaction involved dispatching a security detail to Natural, a shop located on Cularin, the venue of the impending agreement, with the aim of preventing its execution.
In the course of the Clone Wars, Raik Muun, a Dark Jedi, seized a contingent of Culpharm researchers and transported them to her base on Tilnes. There, she compelled them to conduct experiments on the t'salak.